Possible role of the collagen type I alpha 1–platelet‐derived growth factor beta chain fusion gene in the development of dermatofibrosarcoma protuberans with fibrosarcomatous transformation

Dermatofibrosarcoma protuberans with fibrosarcomatous transformation (DFSP-FS) is a rare variant, higher rates of recurrence and metastasis than DFSP. Detection the collagen type I alpha 1 (COL1A1)–platelet-derived growth factor beta chain (PDGFB) fusion gene useful for diagnosis In this letter, we report case DFSP-FS, focusing on expression COL1A1-PDGFB in lesions. Increased may be associated changes during pathogenesis